GHK-Cu Tripeptide for Skin Restoration
Copper peptides are naturally occurring small protein fragments that have high affinity to copper ions. In human plasma, the level of GHK-Cu is about 200 µg/ml at age 20. By the age of 60, the level drops to 80 µg/ml. In humans, tripeptide GHK-Cu can promote activation of wound healing, an attraction of immune cells, antioxidant and anti-inflammatory effects, stimulation of collagen and glycosaminoglycan synthesis in skin fibroblasts and promotion of blood vessels growth. Recent studies revealed its ability to modulate expression of a large number of human genes, generally reversing gene expression to a healthier state. Synthetic GHK-Cu is used in cosmetics as a reparative and anti-aging ingredient.
Recent studies show that GHK-Cu has the ability to regulate biochemical pathways resulting in diverse healing and protective actions. Not only does Copper Peptide stimulate blood vessel and nerve outgrowth, but it also enhances the presence of collagen, glycosaminoglycan synthesis, and elastin within the body. GHK-Cu can also improve tissue repair in the skin, liver, lung connective tissue, stomach lining and it also supports the function of dermal fibroblasts.
Copper Peptide GHK-Cu also referred to as glycl-l-histidyl-l-lysine peptide is a copper complex that is naturally produced in the human body, it has a strong affinity for Copper(ll) and is composed of three amino acids that are found in human blood plasma, saliva, and urine. Copper Peptide is essential to various biological functions in the body, such as accelerating wound repair, promoting blood vessel outgrowth, anti-tumor defense, as well as, antioxidant and anti-inflammatory effects. Adults in their 20s posses 200ng/ml of this copper complex, while adults in their 60s only have 80ng/ml, indicating that the levels of Copper Peptide GHK-Cu drop during the aging process.
The medical study of Copper Peptide GHK-Cu began 48 years ago in the 1970s, since then medical researchers have made groundbreaking discoveries regarding its molecular actions and biological processes. Copper is a transitional metal that is critical to human survival. It operates as an extraordinary factor in a plethora of biochemical reactions. GHK-Cu’s unique ability to bind with Copper (ll) ions makes it an important role in copper metabolism. The relationship between Copper (ll) ions and Copper Peptide GHK-Cu allows GHK-Cu to modulate gene expression and regulate human genes.
Clinical Trials and Studies
In 1994, doctors discovered that the application of a 2% GHK-Cu gel on diabetic patients was enough to enhance the percentage of ulcer closure from 60.8% to 98.5% and decrease the percentage of infections from 34% to 7%.
Numerous controlled facial studies confirm that Copper Peptide is an essential element that can be used to firm and tone skin, likewise, reduce wrinkles and the facial aging process. Doctors found that GHK-Cu amplified collagen in the photoaged skin and demonstrated remarkable improvements in skin laxity, clarity, and overall appearance.
Further clinical studies highlight the efficiency of synthetic analog found in Copper Peptide used to stimulate hair growth.
Researchers believe that the presence of Copper Peptide in the body can stimulate the proliferation of keratinocytes and increase the expression of integrins and P63 protein in the epidermal stem cell resulting in its ability to revive proliferative prospects of epidermal stem cells and heighten their ability to repair tissue within the body.
Benefits of Copper Peptide GHK-Cu
Copper Peptide is a small molecule that holds many health benefits such as:
1. Skin Restoration
GHK-Cu is a key ingredient in cosmetic products used to reduce the signs of aging by firming and toning the skin, removing deep wrinkles and lines on the face, reduce skin spots and lesions and improve the overall skin appearance.
2. Stimulate Wound Healing
GHK-Cu is produced naturally in the body. It is found in human plasma and is released from the tissues when physical injuries occur. It’s regenerative properties and anti-inflammatory effects accelerate wound repair and healing. Patients are encouraged to use GHK-Cu after surgery to reduce scarring and advance the healing process.
3. Reduce Pain, Aggression, and Anxiety
Apart from its antioxidant and anti-inflammatory effects, GHK-Cu physical structure resembles Cimetidine, a component that is used to reduce pain.
4. Hair Re-growth
As mentioned earlier, Copper Peptide GHK-Cu strongly stimulates hair growth by increasing follicle cell proliferation and decreasing programmed follicle cell death.
5. Anti-Cancer Effects
GHK-Cu is capable of reversing the expression of specific genes associated with the metastatic spread of colon cancer.
Copper Peptide GHK-Cu has been studied by doctors and researchers worldwide for over 40 years. It’s biological effects have been proven through research studies and clinical trials on humans, as well as lab rats. GHK-Cu is naturally produced by the human body and is safe to administer as a serum or microneedle treatment. It’s antioxidant and anti-inflammatory effects, as well as, its ability to amplify collagen, elastin and glycosaminoglycan synthesis, repair tissue and regulate human genes makes it a prominent medical breakthrough.