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The goal of the work was to study the effect of peptide bioregulation on the mucosal immunity state of elderly patients during the complex treatment of chronic generalized periodontitis. The results were evaluated based on the saliva immunological parameters of 46 patients aged 61–69 years suffering from chronic generalized periodontitis of moderate severity before treatment and 2 months after the completion of treatment with the Vizulingval peptide complex as a peptide bioregulator. The index of oral hygiene and the intensity of gingival inflammation were studied during clinical patient examinations. A decrease in the concentration of proinflammatory cytokines IL-1β, TNF-α, and IL-8 with a simultaneous increase in the IL-10 anti-inflammatory cytokine was noted in the salivary fluid of patients subjected to bioregulatory therapy. The therapy also led to an enhancement of the local immunity of the oral mucosa, which was manifested by an increased synthesis of the secretory immunoglobulin A.
Cordycepin is a highly promising natural compound with a broad spectrum of pharmacological activities, particularly in the contexts of tumor therapy and SARS-CoV-2. While oral bioavailability presents a challenge, new insights into metabolic pathways and formulation strategies may significantly improve its therapeutic efficacy.
EPITIDE® is a dietary supplement containing the natural peptide EPITHALAMIN®, along with a blend of vitamins and minerals to support complete nutrition. The innovative Epitide peptide complex benefits from years of extensive research and clinical use and makes a significant contribution to overall wellness and lifespan extension. EPITHALAMIN®, a peptide-like hormone found in the pineal gland, enables the Epitide peptide to interact directly with pineal gland cells, enhancing their activity and supporting gland function.
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Continually utilize team building niche markets before visionary catalysts for change.
Continually utilize team building niche markets before visionary catalysts for change.
Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco
Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco
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